| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_195631d22dd7927a82eab008108edc83
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_92205428e0fbc3b39a4bab31a94b5ada
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5958ad9a7c392f9b9f2f968c868f56fa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d87f6cef935195ca156aa67b2015e07 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-06 |
| filingDate |
2006-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2cb248801ef47513804ed40b44deabdb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b635f8db5975ed8dfbd8bb8c13491a02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c66f8dd4db6c7d3b5bbe0f4ec3da687 |
| publicationDate |
2007-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2007004237-A2 |
| titleOfInvention |
A process for the preparation of montelukast |
| abstract |
The present invention relates to a process for the preparation of Montelukast or a salt thereof comprises, i) condensing Methyl -2-[3-[3-(2-(7 - chloroquinolin -2-yl) ethenyl] phenyl] -3 -chloro propyljbenzoate obtained above with l-(mercaptomethyl) cyclopropane acetic acid in presence of alkali carbonates such as Cesium Carbonate, followed by salification with organic amine ii) neutralizing the organic amine salt as obtained above with organic/inorganic acid followed by reaction with methylmagnesium chloride in the presence of Cerium Chloride followed by treatment with organic base yields montelukast amine salt iii) converting the montelukast amine salt to Montelukast Free acid iv) saltification of Montelukast free acid with Sodium hydroxide affords Montelukast Sodium. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7812168-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008062478-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008062478-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008015703-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8617853-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103080085-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011121091-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011004298-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102164897-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009016191-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8115004-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8163924-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009053424-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013532723-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8088610-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8188285-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103772275-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103772275-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8178680-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2053043-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103080085-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007096875-A3 |
| priorityDate |
2005-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |