http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006138377-A9
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_15194be5de3192662f7e5a7897df3fe4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_848636199aeaf2efd6b9208badb30e0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_09fc02a407043ca0a10e2dbe5fcb6159 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e071d18fea054bf8d1420d483e78ed1 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 |
| filingDate | 2006-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0491dafbcab17e6ff3856219b7ab331e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa8c25d2937a3068c84329bad1905c1f |
| publicationDate | 2007-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2006138377-A9 |
| titleOfInvention | Compound combinations for inhibiting cell division and methods for their identification and use |
| abstract | The present invention provides in vitro assays, e.g., FtsZ GTPase assays, and/or in vivo assays and methods of use thereof to identify particular compounds and combinations of compounds that affect microbial cell division. The invention further provides such compounds and compound combinations, including combinations that result in inhibition of cell survival or growth when present together at concentrations below their individual MICs. Certain of the compound combinations display synergism. Certain of the combinations include a compound that inhibits FtsZ GTPase activity and a compound that inhibits cell growth by a mechanism other than inhibition of FtsZ GTPase activity. The present invention further provides pharmaceutical compositions that have anti-microbial activity and methods of treating microbial infections. |
| priorityDate | 2005-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 366.