Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5cfe98a332d8fd8ab0da97094b452a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f83d6e2efdce18a676ee2392b3fceda7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bfe5d59fd6b14c02afc38a0af2583c78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_73f7c698eaadc9ea62b8de72cabf42b9 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-01091 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-99 |
filingDate |
2006-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31896ae8d3df264fc745021844d16559 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad524efcb59861b40fe46b2d29a30fbc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa2e573892bf2012da64923b7d0d8867 |
publicationDate |
2006-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2006135968-A1 |
titleOfInvention |
Modulation of sphingosine kinase signalling |
abstract |
The present invention relates generally to a method of modulating cellular activity and to agents for use therein. More particularly, the present invention provides a method of modulating the level of sphingosine kinase functional activity. In a related aspect, the present invention provides a method of modulating sphingosine kinase mediated signalling via modulation of its intracellular level of activity. The present invention still further extends to novel molecules which exhibit the capacity to induce sphingosine kinase activity. The methods and molecules of the present invention are useful, inter alia, in the treatment and/or prophylaxis of conditions characterised by aberrant, unwanted or otherwise inappropriate cellular functional activity and/or aberrant, unwanted or otherwise inappropriate sphingosine kinase mediated signalling. The present invention is further directed to methods for identifying and/or designing agents capable of modulating the level of sphingosine kinase activity. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2166094-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1910525-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1910525-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8324237-B2 |
priorityDate |
2005-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |