| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_48dcce6ae8c7dfed2cd88b7c9ff63ec7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e1dbd49e062bd39999dc27e542cb8d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_362c7fb76037b92c4235b0d64abed3cf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f7154c77108d36fce58d4814c1e17eac |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-585
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4184
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-401
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-556
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-08 |
| filingDate |
2006-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22052034bea84ffde0dcab469e10c688
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66f6aa87025a465ad1203566da232591
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d38015c1154a1323c73da98b95dcbc4 |
| publicationDate |
2006-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2006135621-A2 |
| titleOfInvention |
Method for renin-angiotensin-aldosterone system activation and control thereof |
| abstract |
An improved blood substitute composition comprising a blood substitute and a renin-angiotensin-aldosterone system inhibitor. A method of treating a patient having a disorder requiring a blood transfusion comprising administering a free hemoglobin based blood substitute and a renin-angiotensin-aldosterone system inhibitor. A renin-angiotensin-aldosterone system activator comprising hemoglobin or hemoglobin and a peroxide. A method of increasing the activity of angiotensin converting enzyme comprising incubation with hemoglobin or hemoglobin and peroxide. A method according of activating the renin-angiotensin-aldosterone system comprising contacting in vivo a free hemoglobin based blood substitute with a peroxide wherein the product induces the production of angiotensin I metabolites which comprise metabolites capable of affecting the vascular tone and/or stimulating aldosterone production. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103690954-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103690954-A |
| priorityDate |
2005-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |