Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d2ad4c6499a8eb6733e5107a6a060452 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5e9a32996d2c8093497f218dd9801de2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_94cc083991180fab007278ceb20f0993 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_259045c6eba6e2c5d338b84e0a88b571 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_901588c5fd7e694d395d427b1975b88f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_010cfd10237b8472a5de383b1128e42e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-998 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0646 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0783 |
filingDate |
2005-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_608f0b81109fb41e32affe9977acfaec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f9b5f8fc85abab76332982cebf86c11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9230f96482bcc8f10e2c78fcd64a9b60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d051979b406edcc4309abb3d46b1307c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23d9e8d380d8e796a072e691a8bdf156 |
publicationDate |
2006-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2006132448-A1 |
titleOfInvention |
An agent for differentiating hematopoietic stem cell into natural killer cell comprising vdup1 protein or gene edcoding the same, and a method of differentiating hematopoietic stem cell into natural killer cell using thereof |
abstract |
The present invention is related to an agent for differentiating hematoietic stem cell into natural killer cell comprising VDUP1 protein or gene encoding the same, and a method of differentiating hematopoietic stem cell into natural killer cell using thereof. The present invention reveals for the first time that the VDUP1 gene is a critical factor for the regulation of differentiation of natural killer cell by generating a mouse deficient in VDUP1 gene, which confirms that VDUP1 gene is required for NK maturation. Thus, by the regulation of VDUP1 gene, the modulation of NK cells that have ability to kill cancer cells is possible and can be utilized for cell therapeutics. |
priorityDate |
2005-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |