http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006131790-A3

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filingDate 2005-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_656dea8284906fa95e97e9867e2ba6ba
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publicationDate 2007-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2006131790-A3
titleOfInvention Oral ribavirin pharmaceutical composition
abstract The invention relates to oral pharmaceutical compositions for the prevention and/or the treatment of viral diseases. This invention also addresses methods of prevention and/or treatment of these viral diseases, using thèse oral compositions. One of the main problems considered in the present invention, is to enhance the efficiency of anti-viral treatments, especially against Hepatitis C by means of ribavirin, for example in combination with interferon. The oral ribavirin antiviral composition according to the invention increases the bio-absorption time of ribavirin, and thus improves the treatment of the patients. Said composition comprises at least one modified release form of ribavirin which bio-absorption time BAT is greater than the bio-absorption time BAT* of a reference* immediate release form of ribavirin administered at the same dose; BAT being preferably comprised between 2 and 15 hours and more preferably between 4 and 12 hours. Said composition is a reservoir type form or a matricial type form. Said composition is a gastric retentive System or a multiparticulate form.
priorityDate 2005-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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