| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_13091234cd69e7a07650781f53a5ef5c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8b44caeacd03f5c1ef6df47bf94cd006
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18b8ba4d5a4d236b0baa946e7f1bd8a3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b6121dedd894b3f760906b68697d616
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_229a9329cc55d13438d14019c91d9388 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-107 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0066
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
| filingDate |
2006-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b1a1aaf07421bbc5a61f9d2435ed595
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8ec74ef65a4522c2d001ba2c2657ba8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9dd94a907a48ae2e3f2fa91275c47243 |
| publicationDate |
2006-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2006130581-A2 |
| titleOfInvention |
Methods for delivering genes |
| abstract |
Methods of delivering transgenes to target cells using plasmids comprising viral inverted terminal repeat (ITR) sequences are described. Such plasmids are capable of directing sustained transgene expression in target cells in rats provided that at least one adeno-associated virus (AAV) ITR sequence is present in the plasmid, regardless of whether that ITR is located upstream or downstream of the transgene. In a particular embodiment, plasmids comprising one or more AAV ITR sequence and an IL-10 transgene are shown to be effective in sustained reversal of pain in an animal model of neuropathic pain. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111886343-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9896665-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11634742-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012158757-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10512672-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019165050-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11273227-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9249425-B2 |
| priorityDate |
2005-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |