abstract |
The invention relates to medicine and veterinary sciences. The inventive method for increasing longevity and retarding sickliness occurrence along the age increment consists in administrating an extracellular blood DNA (ECDNA) inactivating agent in a systemic circulation. Said agent is embodied in the form of an ECDNA-DNAse enzyme-destroying agent, or an ECDNA-anti-DNA antibodies bonding agent, which modifies the ECDNA-chemical composition and/or conformation and/or polymerity without destruction thereof, or an agent stimulating the synthesis and/or activity of endogenic biopolymers which bound or destroy or modify the ECDNA-chemical composition and/or conformation and/or polymerity without destruction thereof. Said method makes it possible to exclude a direct action on the ageing cell genetic apparatus and to retard the following processes: reduction of a sexual activity, reproducibility, cognitive and mnestic functions, stress resistivity, modification of the organism glucose nonresponsiveness and the development of organ and tissue sclerosis. |