| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_268b07e43083c09e5458b7c08dae4837
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_797d0fdb51b9056485169b0151d1688d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c412e514bf4f06993341d71463fe6f70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c30b29942b9d4f7e357e72b1cfb85cb5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_686da5c2b10a201e417fa105e8f5368c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-13 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713 |
| filingDate |
2006-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fad6daa6cd4097e68dd0ebeea96a2a80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a9f4923c1a0c9413dca678c6323af15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3874e8bc46271b57856e70688589d90 |
| publicationDate |
2006-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2006117600-A2 |
| titleOfInvention |
Double-stranded synthetic oligonucleotides useful for inducing apoptosis of osteoclasts for the treatment of osteopenic pathologies |
| abstract |
The invention relates to a synthetic double- stranded oligonucleotide capable of modifying the molecular phenotype of osteoclasts and increasing the expression of the oestrogen alpha receptor gene. Pharmaceutical compositions comprising the oligonucleotide according to the invention are also described, as well as therapeutic applications of that oligonucleotide, in particular for the treatment of osteopenic diseases such as for example osteoporosis . The oligonucleotide according to the invention is characterised in that it comprises the sequence 5'-ATTTATTTTCAATACTGACT-3' or a fragment or a mutant thereof . |
| priorityDate |
2005-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |