http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006115237-A1

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filingDate 2006-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_827b3dff0eb6407f85fc0fa6417badf9
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publicationDate 2006-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2006115237-A1
titleOfInvention Process for producing 4-amino-2-alkylthio-5-pyrimidinecarbaldehyde
abstract An industrially advantageous process for 4-amino-2-alkylthio-5-pyrimidinecarbaldehyde production by which a 4-amino-2-alkylthio-5-pyrimidinecarbaldehyde can be easily produced in a high yield; an intermediate compound for use in the process; and an industrially advantageous production process by which the intermediate compound can be easily and safely produced in a high yield. A process for producing an alkali metal salt of a 3,3-dialkoxy-2-hydroxymethylenepropanenitrile is provided which is characterized by reacting at least one nitrile compound selected from the group consisting of 3,3-dialkoxypropanenitriles and 3-alkoxy-2-propenenitriles with a formic ester at -10 to 30°C in the presence of a base containing an alkali metal. Also provided are: an alkali metal salt of 4-amino-2-mercapto-5-pyrimidinecarbaldehyde; a process for producing the alkali metal salt of 4-amino-2-mercapto-5-pyrimidinecarbaldehyde which is characterized by reacting the 3,3-dialkoxy-2-hydroxymethylenepropanenitrile alkali metal salt with thiourea; a process for producing a 4-amino-2-alkylthio-5-pyrmidinecarbaldehyde which is characterized by reacting the 4-amino-2-mercapto-5-pyrmidinecarbaldehyde alkali metal salt with an alkylating agent; and a use of the 4-amino-2-mercapto-5-pyrimidinecarbaldehyde alkali metal salt in producing the 4-amino-2-alkylthio-5-pyrimidinecarbaldehyde.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006321749-A
priorityDate 2005-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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