| abstract |
Disclosed is a 2-aminobenzimidazole derivative which is effective for a disease cause by abnormal serum uric acid level. A 2-aminobenzimidazole derivative represented by the general formula (I) or a prodrug thereof or a pharmacologically acceptable salt of the compound or prodrug or the like; or a pharmaceutical composition comprising the compound, prodrug or salt as the active ingredient; or the like. (I) wherein R1 represents a halogen atom or the like; m is an integer of 0 to 2; n is an integer of 1 to 2; R2 represents OH or the like; R3 and R4 dependently represent H or OH; the ring Q represents a heterocyclic ring or a bicyclic hydrocarbon group; R5 and R6 independently represent a cyano group, -AH, -A-D-E-G or the like (where A represents a single bond, O, S, NR8 or the like; D represents an alkylene or alkenylene group which may be substituted or the like; E represents a single bond, O, S, NR9 (where R8 and R9 independently represent H or an alkyl group which may be substituted), a (hetero)cycloalkylene or (hetero)arylene group which may be substituted or the like; G represents H, an alkyl or alkenyl group which may be substituted or the like); R7 represents H, a halogen atom, a (hetero)aryl group which may be substituted or the like. |