http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006113981-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8960a6949c97c77894d86c45ce223de2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12188b76916a70ef72cf300e45e79fd2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9053336f864c5a26dbb215cf18470db1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7d78b6492e3672ec504ebc366fc2963 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_95a19bd5f084373411966e2ac84e2176 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9b0460066edadb0850b8be63cc81983c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D407-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D407-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D407-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D407-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D407-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D407-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-36 |
| filingDate | 2006-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15024e8f21886ccaececa205b4084f0b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6923786d2d8ec8842733d4868aa73f9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f528cb3c0f5d182b95b55bdb3b4454f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa4c36f90429f3c4731cdc644e297d90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a62ac5ed8b550414f7dc7f142eeb43f7 |
| publicationDate | 2006-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2006113981-A2 |
| titleOfInvention | Process to obtain dibenzylbutyrolactonic, tetrahydrofuranic lignans and their synthetic and semi-synthetic derivatives, their analgesic and anti-inflammatory activities, topical and/or systemic formulations containing said lignans and their respective therapeutic method |
| abstract | The present invention refers to a process to obtain dibenzylbutyrolactonic lignans form (-)- cubebin, insolate from a Piperaceae, especially Piper cubeba, and from (-)-methylpluviatolide insolated form a Rutacea, especially Zanthoxylum naranjillo; their synthetic and semisyntheti derivatives and tetrahydrofuranic lignans, such as glagravin and veragensin, insolated form Nectandra meapotamica, as well as the analgesic and anti-inflammatory activities of said lignans, and the topical and/or systemic formulatins where lignans present 60 to 80% of the formulation. The invention also refers to a therapeutic method using topic and/or systemic formulations based on said lignans for the treatment of inflammation and/or pain. More specifically, it refers to a process to obtain synthetic and semi-synthetic derivatives of (-)- cubebin such as: - -O-acet l cubebin; - -O-meth l cubebin - -O- N N-dimeth lamino-ethyl)- cubebin; (-)-hinokinin; (-)6,6'-dinitroinokinin; (-)-o-benzyl cubebin; (-)-6,6'-diaminohinokinin and other synthetic derivatives which may be obtained, and synthetic and semi-synthetic derivatives of (-)-methylpluviatolide, such as (-)-6,6'-dinitromethylpluviatolide and (-)6,6'- diaminomethylpluviatolide, to be used in the manufacture of medicine that has analgesic and anti-inflammatory activity. The present invention also refers to the process ot obtain the substances glagravin and veragensin islated from Nectandra megapotamica, as well as their synthetic and semi-synthetic derivatives with substituents on the aromatic rings that may be obtained. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014086379-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8829049-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011075801-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102451178-A |
| priorityDate | 2005-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 117.