Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e0977ba882c387d8587a861c8791809 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2053083f1fbfb1dd2d3c212a4eeac3a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_183ce05c31b6110e7a36255cb5868045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f3f44c7b7bd89b3932404162e6d02118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7dc89a3389bc31f64ad3cadc66bc91ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_35a392f3f9b9999897e49ffd7afea363 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b74695f4c6259a8598b722c1ef6eefa |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y305-01098 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-50 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46 |
filingDate |
2006-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3773cf586b0d4ca3bf664d7a8c25fbdb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_051fb34dccac4d9744df9f64a3b3269b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ab6c7b33a6e54235b77d2fc97b41f39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_effa02d1535a0b0ba0d7cf37a54a583e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19975360584fd0f4e6ec7182db4f85f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a9aba62e4b96763cb81eaa5458b8d61 |
publicationDate |
2006-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2006111596-A1 |
titleOfInvention |
Use of hdac6 protein tubulin deacetylase activity agonist compounds in the preparation of pharmaceutical compositions, said pharmaceutical compositions and applications of same in the treatment of viral infections |
abstract |
The invention relates to the use of HDAC6 protein tubulin deacetylase activity agonist compounds in the preparation of pharmaceutical compositions, to said pharmaceutical compositions and to applications of same in the treatment of viral infections. The invention is based on the fact that the acetylation/deacetylation equilibrium of the microtubules is key for modulating the entry of fusogenic viruses into eucaryotic cells, preferably the entry of the HIV-1 virus into T cells, and which is regulated by the HDAC6 protein, thereby enabling novel therapeutic approaches to be defined for the prophylactics and treatment of viral infections. The aforementioned therapeutic approaches are based on the use of compounds that activate the activity of the HDAC6 protein and of the pharmaceutical compositions that contain same in methods for the treatment of said viral infections. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010045224-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2100879-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3154579-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010045224-A2 |
priorityDate |
2005-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |