| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f16a6d8b1582fd7a69644084ed7aa3c9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b356d59778b04fee848fdf8af71dbfee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e1200e8df9355c9efb56cf78db2c5c9 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-24222
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0337
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
| filingDate |
2006-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94c9b2589a16315f87246f1ef627a46f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80f1c1fc021aa9514fb3a086578756a3 |
| publicationDate |
2006-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2006109196-A2 |
| titleOfInvention |
Transgenic mouse models of hepatitis c virus (hcv) and identification of hcv therapeutics |
| abstract |
Disclosed herein is the discovery of novel NS3/4A compositions with enhanced expression abilities. Embodiments of the invention include codon optimized NS3/4A compositions and compositions with the Semliki forest virus replicon. Additional embodiments include transgenic organisms containing these NS3/4A compositions, methods of using these transgenic mice to screen and refine drugs, and the drugs refined by these methods. Additional embodiments include protease activity dependent molecules that can indicate the presence or absence of a protease inhibitor. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013147649-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8987302-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8912141-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008150899-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012038950-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012176149-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9321847-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013147649-A2 |
| priorityDate |
2005-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |