| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e19741e967ed6c909c17813b4f9ef63e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_40cbec1126e93ce256616e629cad7328
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9274afbbcdaace0e8f907634f25e7463 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-04 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7068 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7068
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2006-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_121c9e297330cdfd9a2ecaabf53629cc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecf536da3f6b99561cd917db9bbe1c19 |
| publicationDate |
2006-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2006109091-A2 |
| titleOfInvention |
Sensitisation of cancer cells to dna replication inhibitors |
| abstract |
This invention relates to the characterisation of the activity of the RECQL4 protein and the recognition that deficiencies in RECQL4 activity sensitise cancer cells to drugs which inhibit DNA replication. Methods of identifying RECQL4 deficient cancers which are sensitive to drugs which inhibit DNA replication and methods of treating RECQL4 deficient cancers using such drugs are provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011058408-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106191071-A |
| priorityDate |
2005-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |