Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d21b204115942b5a2b8a4ec8953d18d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_98510a9ad48bc9b98e49491b39c425bc |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-03 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0276 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 |
filingDate |
2006-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6544569ece5ae51cc15b4e587a580f63 |
publicationDate |
2006-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2006108234-A1 |
titleOfInvention |
Modified animal lacking functional pyy gene, monoclonal antibodies that bind pyy isoforms and uses therefor |
abstract |
The present invention provides transgenic animals having a reduced level of expression of peptide YY (PYY) and drug screening platforms using the transgenic animals for identifying agonists and antagonists of PYY. The present invention further provides monoclonal antibodies that bind specifically to full-length PYY[1-36] or the processed form thereof i.e., PYY[3-36] and to diagnostic and drug screening platforms using the monoclonal antibodies. The invention has particular utility for the diagnosis of a predisposition or risk of a subject becoming obese, developing one or more pathologies associated with obesity, or developing a disease/disorder of bone tissue. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11629185-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111315213-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013078511-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8906849-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013014269-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1789440-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1789440-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8603969-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8426361-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111315213-A |
priorityDate |
2005-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |