Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97eebbc54c764f58382711dd2311b724 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_459549086df37b5bed0003502de7e7aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad6b0148afa0a19246e1a9bc202c72d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9fb78d1d2975267ea4a52b862745f430 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00 |
filingDate |
2006-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6339b352af5e98d216f36fe2e229970f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb58930c3c4612195cbfaf167c811b4e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77f1751a0cbc22db33180a9e8b4c7ae2 |
publicationDate |
2006-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2006106529-A1 |
titleOfInvention |
A co-spray dried composition of cefepime with base and process for preparation thereof |
abstract |
Stable and sterile composition of cefepime and a process for preparing the same. Amorphous composition containing cefepime acid addition salt or solvates thereof and organic or inorganic base obtained by spray drying of their aqueous solution. The process comprises dissolving a composition containing mixture of cefepime acid addition salt and a pharmaceutically acceptable non-toxic organic or inorganic base in water to obtain aqueous solution, filtration of aqueous solution through 0.2 micron membrane filter and subjecting the clear aqueous solution to spray drying, or dissolving a cefepime acid addition salt in water, dissolving a pharmaceutically acceptable non-toxic organic or inorganic base in water, addition of solution from operation (v) to solution from operation (iv) at 0-30°C, preferably at 0-10°C to obtain a solution having a pH in the range of 3.0-7.0, filtration of aqueous solution through 0.2 micron membrane filter, and subjecting the clear aqueous solution to spray drying. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102382125-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011078831-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8614315-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114042048-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114042048-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011139249-A3 |
priorityDate |
2005-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |