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publicationDate 2006-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2006106383-A1
titleOfInvention Photosensitizers and mri enhancers
abstract The present invention relates to the use of a compound of formula (3) or a salt thereof for the manufacture of a medicament or phototherapeutic agent for the treatment of acne, Aids, viral hepatitis, diabetic retinopathy, infection with sars virus, coronary artery stenosis, carotid artery stenosis, intermittent claudication, Asian (chicken) flu virus, cervical dysplasia or cancer of the blood, cervix, naso­ pharynx, trachea, larynx, bronchi, bronchioles, bladder, esophagus, stomach, rectum, colon, prostate, hollow organs, bile duct, ureter, kidney, uterus, vaginal or other female adnexa. The invention also relates to methods of treating these diseases. The present invention further relates to the use of a compound of formula (3) or a salt thereof for the manufacture of a photodiagnostic agent for the detection of the above diseases, as well as atherosclerosis, multiple sclerosis, diabetes, arthritis, rheumatoid arthritis, a fungal, viral, chlamydial, bacterial, nanobacterial or parasitic infectious disease, HIV, hepatitis, herpes simplex, herpes zoster, psoriasis, a cardiovascular disease, or a dermatological condition. The invention also relates to methods of detecting these diseases by photodiagnosis. The present invention further relates to a method of cold sterilising a surgical or other device, comprising the steps of: providing a compound of formula (3) or a salt thereof on the device and subjecting the device to irradiation or sound. The present invention further relates to a compound of formula (3) or a salt thereof, linked or attached to a magnetic element. Such a compound may be used as an MRI enhancer. The present invention also relates to a method of carrying out an MRI scan using such an MRI enhancer.
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