| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8671de9408ed3253f3475547a6717f46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a1d1be6200bb60f340e388868edadc71
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d93a3fdd031e483c033ce2641aca024b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6c14c8dcdeecf04f3da4344749163843
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7b56f8e9a6b41d26bfb8f3da696c09d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6796d32c206b8a614b3e307b25a12328
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_942fddb08dba3d39ec3f742f9903c30b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_66bce9cb071741961f540cff6c647803
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_428dff815117552ee70287dd153805cb |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-525
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2730-10122 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-706
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 |
| filingDate |
2006-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86bc2c3936f75788e7b4420290415486
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb2017b8baaa098114b641cc5a973bda
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4fb43d6464e53928f9a6ed21504ca681
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6bbbfaf4503ce673066658b61b018a5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0756478e7957c21c131cf40b97845b2a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae4a3a9d285a22d07da847d8a89e6c52 |
| publicationDate |
2006-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2006105597-A1 |
| titleOfInvention |
Variants of hepatitis b virus with resistance to anti-viral nucleoside agents and applications thereof |
| abstract |
The present invention relates generally to viral variants exhibiting reduced sensitivity to particular agents and/or reduced interactivity with immunological reagents. More particularly, the present invention is directed to hepatitis B virus (HBV) variants exhibiting complete or partial resistance to nucleoside or nucleotide analogs and/or reduced interactivity with antibodies to viral surface components including reduced sensitivity to these antibodies. The present invention further contemplates assays for detecting such viral variants, which assays are useful in monitoring anti-viral therapeutic regimens and in developing new or modified vaccines directed against viral agents and in particular HBV variants. The present invention also contemplates the use of the viral variants to screen for and/or develop or design agents capable of inhibiting infection, replication and/or release of the virus. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9682109-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013052006-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007140522-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007045045-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8859198-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9932646-B2 |
| priorityDate |
2005-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |