abstract |
The invention concerns a compound of formula (I), wherein: R3 represents a hydrogen atom; and R1 and R2 form together, with the carbon atoms bearing them, a benzene, naphthalene or quinoline ring, each of said rings being optionally substituted, or R1 represents a hydrogen atom, and R2 and R3 form together, with the atoms bearing them, a benzene, naphthalene or quinoline ring, each of said rings being optionally substituted; n represents 1 or 2; -X- represents a group selected among -(CH2)m-O-Ak-, -(CH2)m-NR4-Ak-, - (CO)-NR4-Ak- and -(CH2)m-NR4-(CO)-; m represents an integer between 1 and 6 inclusive; Ak represents an optionally substituted alkylene chain; and R4 represents a hydrogen atom or an alkyl group; Ar represents an aryl or heteroaryl group; its optical isomers, as well as a pharmaceutically acceptable acid-addition salt thereof. The invention is applicable to medicines. |