| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_857f8336175d4a3144facf2e9ad3998b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e10e87af22712f5219a7d2ff1cbb10ea |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2730-10122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2730-10121
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-106664 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-706
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-02 |
| filingDate |
2006-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c27350e113ab4ebe02fce3d77249b712 |
| publicationDate |
2006-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2006097285-A1 |
| titleOfInvention |
Hepatitis-b viral variants with reduced susceptibility to nucleoside analogs and uses thereof |
| abstract |
The present invention relates generally to the field of Hepatitis B variants exhibiting a reduced sensitivity to nucleoside analogues, both in vivo and in vitro. More in particular, reverse transcriptase mutant rtA181S is provided. Present invention provides assays and methods for detecting such variant, which assays are useful in monitoring anti-viral therapeutic regimes and adjusting patient therapy. A diagnostic kit for detecting the presence of an HBV variant in a biological sample has also been described. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009213465-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10376576-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10898567-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20170008873-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102569204-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015187009-A1 |
| priorityDate |
2005-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |