| abstract |
This invention provides aryl and heteroaryl compounds of formula (X). The compounds of the invention may be useful as antagonists, or partial antagonist of factor IX and/or factor Xl and thus, may be used to inhibit the intrinsic pathway of blood coagulation. Formula (X) wherein R102 is selected from the group consisting of -C(O)OH, -C(O)OCH3, -C(O)O-t-butyl, -C(O)NH-OCH2-phenyl, C(O)NHOH, and -C(O)NHSO2CH3; and wherein R101 .R103,R104 and Y are as defined herein. |