Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_946bb0e58a06b4019c3ee10d37d64de7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ffc114114a3a475991c713874eca1ea7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d595ec481a2a081fed4aa2fd4ff52d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_de31602cd2deecc65b9d695220c26ccc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c4d4e7ff903ccaf3de92d8d12c067654 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 |
filingDate |
2006-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a18fb4ed09157d2c2f684a77f71aa1fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c17d739abd61157c71f848d720dcf76a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_330cd98a3714bc79301034686a33245d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b40665a01133b82ba7b3a845e679e7ea |
publicationDate |
2006-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2006084043-A2 |
titleOfInvention |
Novel chloride channel pore openers |
abstract |
Described is a method for treating and/or preventing disease states and conditions associated with defects in the activity of chloride channels, such as the CFTR channel. The present disclosure also described compounds useful in such treatment and prevention methods and methods for the identification of compounds for use in such methods. These compounds disclosed are NPPB, NPPB-Am, NPPB-sulf and curcumin, and derivatives of the foregoing. These compounds are shown to activate the activity of both wild-type and mutant CFTR channels under a range of conditions. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IT-RM20090315-A1 |
priorityDate |
2005-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |