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publicationDate 2006-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2006083945-A2
titleOfInvention Rnai-mediated inhibition of ocular targets
abstract RNA interference is provided for inhibition of ocular hypertension target mRNA expression for lowering elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Ocular hypertension targets include carbonic anhydrase II, IV, and XII; β1- and β2 adrenergic receptors; acetylcholinesterase; Na+/K+-ATPase; and Na-K-2Cl cotransporter. Ocular hypertension is treated by administering interfering RNAs of the present invention.
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5460005
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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID239788585
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID239893386
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP36196
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID136062818
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226414226
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID239893388
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP27139
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID39468
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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID452892474
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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID240904192
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http://rdf.ncbi.nlm.nih.gov/pubchem/taxonomy/TAXID272636
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http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID43
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID18594011
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ7LZG1
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http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID154
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP07692

Total number of triples: 369.