Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_683cccaab594f16358544103539682dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e696113d0c1daad25bf8f1fe732dc408 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_258ff8776ea6eb10e054ff358cb79345 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d70aec27d6def7944380046d5f07cab3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_186922462f3cf39d03630b573a97830a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-02 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-164 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-195 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate |
2006-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36d83b2c2e672148b581568f66612914 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_029fc520e7429fb96e2c5fde6b1941e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_506c0eb91ed31d38eb8746ad230141f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b3a5a67d8dea8d43826d0816034f97f |
publicationDate |
2007-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2006083516-A9 |
titleOfInvention |
Modified cyanovirin-n polypeptide |
abstract |
This disclosure relates to a modified version of cyanovirin-N protein and a transformed Lactobacillus bacterium that is capable of recombinantly expressing this modified protein. Further disclosed are polynucleotide sequence encoding the modified cyanovirin-N protein, expression cassette that allows the expression of the modified protein, and method of make and use of the modified protein as well as the transformed Lactobacillus bacterium. In addition, this disclosure describes two novel promoters originated from L. jensenii, which are capable of directing a high level of gene expression in Lactobacillus bacteria. Also described are an expression cassette comprising one of the novel promoters, a genetically modified Lactobacillus bacterium containing the expression cassette, a method for recombinant gene expression in Lactobacillus bacteria using the novel promoters, and a method for delivery of proteins with desired biological activity to a mucosal surface in a human. |
priorityDate |
2005-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |