Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_48022bcf0ac619a10e1dc38cf32683ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8924f1b41c8a63337f5a920d976b9ede http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8f81c6fa05269fed8e8665a8e72778ee |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2006-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9b1c8bd852e82239c7ef93b90616e3e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a4ec4d824f668aeda6547b4ec7298a5 |
publicationDate |
2006-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2006082570-A1 |
titleOfInvention |
Pharmacogenomics of blood pressure lowering agents |
abstract |
A method of determining a suitable blood pressure lowering treatment for an individual comprises a step of assaying a biological sample from the individual for the presence or absence of the C-5312T SNP in a distal enhancer region of the renin gene. The presence of at least one T allele is indicative of an increased response to a blood pressure lowering treatment selected from the group comprising: angiotensin-2-receptor blockers; ACE Inhibitors; aldosterone receptor blockers; and beta-receptor blockers. The absence of at least one T allele is indicative of an increased response to a blood pressure lowering treatment selected from the group comprising: renin inhibitors; calcium channel blockers; and diuretics. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006102177-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006102177-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013045505-A1 |
priorityDate |
2005-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |