Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_656eb38c0deb37eeb9e8691c7dd50618 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da146a9275852b2ca17543e9f385f26e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ea89ab65592e3d94eda79de4ee007a1c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cbc5b09bb0acf1d76a969b7f38f90351 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1676 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 |
filingDate |
2005-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8887ed42c220e755ffd881dda81802be http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06bb18da0692d362279f17670c0e5801 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41026ef9b016bbec0e0f0d077f258f6b |
publicationDate |
2006-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2006073503-A1 |
titleOfInvention |
Therapeutic calcium phosphate particles for use in inhibiting expression of a gene |
abstract |
Novel calcium phosphate core particles, methods of making them, and methods of using them as carriers of biologically active material and controlled release matrices for biologically active material are disclosed. The core particles may have a surface modifying agent and/or biologically active material, such as polynucleotide material partially coating the particle or impregnated therein or both. The particles may be used to carry polynucleotide (or oligonucleotide) material that is complementary to a sequence of mRNA that binds to or ligates with and inhibits the expression of particular genes (by blocking translation of the mRNA sequence). The core particles are substantially spherical in shape, and have a substantially smooth surface. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10610469-B2 |
priorityDate |
2001-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |