abstract |
The invention relates to novel tetrahydroquinoline derivatives of formula (I), wherein R<SUP>1</SUP> represents cyclohexyl or cyclopentyl, R<SUP>2</SUP> and R<SUP>3</SUP> each represent methyl or jointly form a cyclobutane, and R<SUP>4</SUP> represents cyclopentyl or isopropyl, the salts and solvates thereof, and the solvates of said salts. Also disclosed are a method for the production thereof, the use thereof on its own or in combinations for the treatment and/or prevention of diseases, and the use thereof for producing medicaments, particularly as a cholesterol ester transfer protein (CETP) inhibitor in order to treat and/or prevent cardiovascular diseases, especially hypolipoproteinemia, dyslipidemia, hypertriglyceridemia, hyperlipidemia, hypercholesterolemia, and arteriosclerosis. |