abstract |
The invention relates to novel methods of preventing, treating, or ameliorating Inflammatory Bowel Disease (IBD), in particular Ulcerative Colitis and Crohn's disease, by administering compounds that are capable of inhibiting human neutrophil elastase (HNE), as well as to the use of said compounds for preparing pharmaceutical compositions for preventing, treating, or ameliorating IBD. Furthermore, the invention relates to pharmaceutical compositions comprising HNE inhibitors and further comprising one or more compounds known to be effective in treating IBD. |