| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b7565e5045e770b262c8e75ca1e1bb4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff52fdf63a2febbf621ee7287f6ba3b4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c06d114257182ee7efd4c696c5fdb836
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69239f10ef860ed2296c1aba1f5f3ec7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a3f4ac681ebbaf7453aadbf52e971b2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3778fd0eebb3be3ce4de66164e26ba24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_36dd281b8e9758ff5bf153919d4ead99 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5064
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5023
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6875 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2005-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b661eabb599d56c27a156356320f5159
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e130b1b309c0cfb9330ccea6bb5cd0ec
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29314f2030d625f03d0d9e1926ad0540
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_225d602a6588e7d8bb734da49a78d3b8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60e8ab4ef9a2349719c9c028132e1812
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20cdd21db9143fb274fb62bb8f80ec50 |
| publicationDate |
2007-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2006069000-A3 |
| titleOfInvention |
Klf2 as a mediator of statin activity |
| abstract |
The present invention is directed to methods for identifying compounds that mimic or inhibit the therapeutic effect of statins. The compounds are identified using assays of the transcription factor KLF2. The invention also includes methods for creating or identifying endothelial cells with low KLF2 activity which will be resistant to statin treatment and for increasing KLF2 activity by transfecting cells with expression vectors. |
| priorityDate |
2004-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |