| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53c2f468dd79ebb86375826ea25d1124
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2174dd7ac8f6855b2b6a2019d2e222ad |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A90-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70514
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70596 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56988
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5094
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5091 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-30 |
| filingDate |
2005-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5972f6b73de845f762b0d6adc19c00ef |
| publicationDate |
2006-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2006067572-A2 |
| titleOfInvention |
A method for diagnosing and monitoring cellular reservoirs of disease |
| abstract |
The invention provides an assay for diagnosing and/or monitoring a viral infection or disease in a patient, the assay including the steps of mixing a sample of leucocytes with a fluorescent cell membrane-permeable dye which stains RNA or both DNA and RNA within the leucocytes; identifying from all the leucocytes at least two of the three major sub-populations of leucoytes selected from the group consisting of monocytes, granulocytes and lymphocytes; determining the fluorescence intensity for each of the identified sub-populations; and comparing the fluorescence intensity of at least two cell sub-populations to each other to obtain at least one of the following ratios: monocytes : granulocytes, monocytes : lymphocytes, and granulocytes lymphocytes. The viral infection may be HIV and the disease may be AIDS. The invention also provides a method of monitoring the cellular viral,parasitic or bacterial reservoir of a patient with a viral or bacterial infection by the steps described above. A, kit for performing the assay or method is also provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3237644-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-3030576-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102154264-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011123070-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016102829-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11054424-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102154264-B |
| priorityDate |
2004-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |