| abstract |
The present invention relates to a method of identifying control sequences responding to an-timicrobial peptides (AMPs), to host cells expressing an AMP and comprising a control se-quence of the invention operable linked to a reporter, and to a method of screening for novel AMPs or AMP-variants having improved antimicrobial activity. Particularly the present inven-tion relates to DNA control sequences, wherein the transcriptional profiles of said control se-quences are regulated by the presence of an antimicrobial polypeptide expressed inside the host cell. |