http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006062975-A2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f82e86ec22b78eff782b36128c82e59b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fddbffb2c81775194bb72f6f50e74208 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_65baf97efdbd26a8f24528feff46b13a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_029116ee41eeec8a03f88a8cddbaa758 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_139cc188d3fce955442ff4fdcc2fb316 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78e27e57822029eb855910b5cfaa2380 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-602 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-60 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-10 |
filingDate | 2005-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_236456de1337fc89817a2df16d5fd39f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aaf476f5d6b1fad7f121368507adb788 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bf9682ead7ca8dbe6b442d8ead8fa9a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d829bcb5a0efe3bf480061483baad78f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56e211adc9b741b9ad8b116e9936f25b |
publicationDate | 2006-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2006062975-A2 |
titleOfInvention | Orienting polymer domains for controlled drug delivery |
abstract | The present invention provides a method for the formation of a medical device that comprises a therapeutic agent and a release region, which regulates the rate at which the therapeutic agent is released from the medical device. The method comprises providing a precursor region that comprises a polymer composition comprising two or more microphage separated polymer domains that are immiscible with one another, and forming said release region by a process that comprises applying an orienting field comprising an electric field, a magnetic field, a mechanical shear field, or a solvent gradient field, or a combination of two or more fields to said precursor region, wherein said field or combination of fields changes the spatial orientation of the microphase separated polymer domains within the release region. The electric, magnetic, mechanical shear or solvent gradient field is of sufficient strength to change the spatial orientation of the microphase separated domains. Moreover, the spatial orientation of the immiscible microphase separated polymer domains affects the rate of release of the therapeutic agent from the medical device. Hence, the present invention is further directed to methods of modulating the rate of release of a therapeutic agent from a medical device. Other aspects of the invention are directed to medical devices fromed from the above techniques. |
priorityDate | 2004-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1681.