abstract |
The invention relates to sulfonamide compounds of formula (I) wherein A, B, R1 and X1 to X3 have the meaning as cited in the description and the claims. For example A is biphenyl, B is 2-morpholin-4-yl-2-oxo-ethyl, R1 is H and X1 to X3 are CH. Said compounds are useful as 11β-HSD1 inhibitors. The invention also relates to the preparation of such compounds as well as the production and use as medicament. |