Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_26b043eb1ce9359be10364d544b0ab8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3c97bb08953916c6b569c4a07c7a46e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c1b14dddf6bca72b702319e919d3087a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2603-86 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C49-747 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-755 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-61 |
filingDate |
2005-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_252765692c36928f06ec51f9c89f9626 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d784cb848396a0be505f5e187708f2d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba0f0a10cc968330237ae84e02d0fe90 |
publicationDate |
2006-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2006050399-A2 |
titleOfInvention |
Synthesis of 1,5-disubstituted-2-hydroxy-gibbatetraen-6-ones |
abstract |
1,5-disubstituted-2-hydroxy-gibbatetraen-6-ones are useful as estrogen receptor modulators and as precursors to estrogen receptor modulators. The current invention provides a method for the synthesis of 1,5-disubstituted-2-hydroxy-gibbatetraen-6-ones from simple indanone starting materials via a Robinson-type annulation followed by an internal alkylation reaction. This invention further describes the novel use of a fluoroethyl substituent as a latent alkylating group for an internal cyclization reaction. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9446047-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10682358-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2014318178-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007081895-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007081895-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10172866-B2 |
priorityDate |
2004-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |