Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c8cbbf2290b3f3a9988da29598baa2c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4b669f8728d6a891f0cfd9d276e28cec http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5f3077812ef80de3b863b8e862e0ca98 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S424-823 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0258 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-245 |
filingDate |
2005-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcc37366493872fad4a13de1ed235083 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6544500c188671b3a17c1c2e5bb8f787 |
publicationDate |
2006-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2006047517-A2 |
titleOfInvention |
Live attenuated bacterial vaccine to reduce or inhibit carriage and shedding of enterohemorrhagic escherichia coli in cattle |
abstract |
The invention provides live, attenuated enterohemorrhagic Escherichia coli (EHEC) bacteria in which the Shiga toxin coding sequences are deleted to abolish Shiga toxin production and one or more of the nucleotide sequences for the bacterial adhesin protein intimin, the locus of enterocyte effacement encoded regulator, and the translocated intimin receptor are mutated to inactivate the activity of the encoded protein(s). This live, attenuated E. coli bacteria is used in a vaccine for reducing or inhibiting carriage and shedding of EHEC in cattle. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109414461-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012052093-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112851769-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9669060-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8414903-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010092511-A1 |
priorityDate |
2004-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |