http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006047251-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97660f6c1d1fde1d7fbdf121a2812f77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4fd6ae1ecc1b77d4a8cd092c34aca1f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2893fcdada46228d353a9bdd98613c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3410d63902abc2a6ac3fc0ca203afed8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-36 |
| filingDate | 2005-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c231ba81431f3787a5b048f1ba88483 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd4bae14d547d7feb6033987e6cba289 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_391f0c964cbeebbf46876dd1386b3555 |
| publicationDate | 2006-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2006047251-A2 |
| titleOfInvention | 3-alkylaryl aspartate compounds and their use for selective enhancement of synaptic transmission |
| abstract | The present invention provides an L-aspartate derivative compound represented by the following structure (I) wherein Ar represents an aromatic group; L represents a linking moiety; R represents hydrogen, alkyl, aryl, or heteroaryl; and ~~~ indicates that the stereochemistry at the 3-position can be R or S. The compounds of the invention are useful for selectively inhibiting EAAT3 and for enhancing synaptic transmission. Additionally, the inventive compounds can be used to treat a patient suffering from Alzheimers disease or a neuropathy or a neurodegenerative disease in which L-glutamate transporter activity is involved in the onset of the disease. |
| priorityDate | 2004-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 220.