| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e056cd3d07728da02bb12211ce3831c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_57df48b0c0f3e613a44fd627f2a02028
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4acdd0549d018610d989d547a44d1dc4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4725 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4725
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2005-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e6be6585a0017d240e7f374a5cf07bf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3bccd82f229f41d760941eef344ef737
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9136525abff3ddb6986354737a80c123 |
| publicationDate |
2006-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2006044933-A2 |
| titleOfInvention |
Compositions and methods for disruption of brca2-rad51 interaction |
| abstract |
Contemplated compounds disrupt interaction between BRCA2 and RAD51, likely by binding to RAD51. Based on the crucial role of the BRCA2-RAD51 complex formation in DNA repair and the role of RAD51 in the control of entry into S-phase from G1, numerous compositions and methods are presented. Among other advantageous uses, contemplated compounds may be employed as protective agents for non-neoplastic cells in chemotherapy before exposure of the cells to a chemotherapeutic drug, and/or as DNA-damage sensitizer for neoplastic cells. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022140860-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9012455-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11168093-B2 |
| priorityDate |
2004-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |