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filingDate 2005-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56435a525c0320e5bd2dc50f0fdb42ea
publicationDate 2006-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2006038206-A3
titleOfInvention Compounds that modulate trh actions and inhibit the trh-degrading enzyme
abstract The invention relates to compounds that inhibit thyrotropin-releasing hormone (TRH)- degrading ectoenzyme and/or enhance, and/or mimic the biological actions of TRH. The compounds find therapeutic application, particularly in conditions involving neuronal cell injury and disturbances in neurobiological function. These compounds are based on a C-terminally extended TRH-structure, wherein the C-terminal extension mainly consists of (D) amino acids.
priorityDate 2004-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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