Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ede5fb24e7427fc38b76476d25907698 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_502aad0394b48b193790f094281ba152 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1024 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 |
filingDate |
2005-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56435a525c0320e5bd2dc50f0fdb42ea |
publicationDate |
2006-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2006038206-A2 |
titleOfInvention |
Compounds that modulate trh actions and inhibit the trh-degrading enzyme |
abstract |
The invention relates to compounds that inhibit thyrotropin-releasing hormone (TRH)- degrading ectoenzyme and/or enhance, and/or mimic the biological actions of TRH. The compounds find therapeutic application, particularly in conditions involving neuronal cell injury and disturbances in neurobiological function. These compounds are based on a C-terminally extended TRH-structure, wherein the C-terminal extension mainly consists of (D) amino acids. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015361136-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023074847-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014096090-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9873717-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2013360758-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016509200-A |
priorityDate |
2004-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |