Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c564991ae13d25b7772e76de8d0160e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_354bc0777afcc4fd4b9218efba1151cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5c9ef208c8453e0a85a84bfbd5d8fdf http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e44b9892acc24cb69b76424b3ddd675d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_faf522b8b83eded745c73018576219ba |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-533 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57423 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2005-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_519a2eae7b7d1a69b673b40dd36dbf80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1dc62c1eb46d1ea993d0d2160baf0a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db6fce9b351aaec895db36faff0a8eca |
publicationDate |
2006-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2006033460-A1 |
titleOfInvention |
Method for diagnosing non-small cell lung cancers by trna-dihydrouridine synthase activity of urlc8 |
abstract |
The present invention features a method for determining t-RNA dihydrouridine-synthase activity of a polypeptide and screening for modulators of t-RNA dihydrouridine-synthase activity. The present invention further provides methods or pharmaceutical compositions for preventing and/or treating non-small cell lung cancer (NSCLC) using such modulators. Furthermore, the present invention provides methods for diagnosing non-small cell lung cancer (NSCLC) using the t-RNA dihydrouridine-synthase activity of IMS-E21 (URLC8) protein as an index. The present invention further provides methods for predicting and prognosing lung squamous-cell carcinoma (SCC). |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2142648-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2142648-A1 |
priorityDate |
2004-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |