| abstract |
Compositions and methods for the treatment, prevention, inhibition, etc, of inflammatory disease or fibrous adhesions involving administration of fucans from various echinoderm sources, alone or in combination with other agents useful for the treatment, prevention, inhibition, etc, of fibrous adhesions or inflammatory disease. The anti-fibrous adhesion agents provide significant therapeutic effect against fibrous adhesions while typically also providing low side effects. Further, since avariety of different anti-fibrous adhesion agents are discussed, various combinations of the agents can be selected as desired to reduce side effects in patients potentially suffering from other diseases or conditions and/or to provide other beneficial healthful or therapeutic effects, such as compositions that both inhibit fibrous adhesions and also treat cancer or arthritis or swelling or any of the variety of other diseases or conditions that can also be treated by one or more of the anti-fibrous adhesion agents herein. The compositions herein are also useful for the treatment of fibrous growths and conditions such as keloid trait that share similar biology with fibrous adhesions. |