| abstract |
Novel polymorphs Forms I, II and III of the potassium salt of Atorvastatin, (βR,δR)-2-(pfluorophenyl)-( β,δ-dihydroxy-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-l -heptanoic acid, are obtained directly by precipitation of the potassium salt of Atorvastatin with ethanol (polymorph I), with 1-propanol (polymorph II) and by recrystallisation of polymorph I from 2-propanol (polymorph III). |