http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006017083-A3
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9aafeb112dac8fb97e43d129e3423983 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dc7991b895704569bb86d70bc0c81ee9 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-154 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2005-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_640e671063ae013db9382b7ff941e2dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_119a20add1e9ee1fba75334907791958 |
publicationDate | 2007-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2006017083-A3 |
titleOfInvention | Methods and compositions for phenotype identification based on nucleic acid methylation |
abstract | Methods and compositions for identifying an unknown phenotype of a tissue that correlates with changes in the methylation state of the tissue comprising, nucleic acid sample from the tissue with a reagent that modifies unmethylated cytosine to produce uracil, amplifying the nucleic acid target gene region using at least one primer that hybridizes to a strand of said nucleic acid target gene region to produce amplified nucleic acids, determining the characteristic methylation state of the nucleic acid target gene region by base specific cleavage and identification of methylation sites and comparing the ratio of methylated cytosine to unmethylated cytosine for each methylation site of the nucleic acid target gene region to the ratio of methylated cytosine to unmethylated cytosine for each methylation site of a tissue nucleic acid sample of the same type having a known phenotype thereby identifying the unknown phenotype. |
priorityDate | 2004-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.