| abstract |
The invention relates to the use of at least one member selected from the group consisting of alpha-ketoglutarate and its salts: ornithyno-alpha-keto-glutarate, asparagine-alpha-keto-glutarate and other salts with amino acids and salts of alpha-keto-glutarate with metal ions such Na, Ca, Mg, Cu, Sr, Zn, K and others in doses 0.001-1 g/kg/day or in concentration 0.001 mM-100mM for the manufacture of a pharmaceutical preparation and/or food/ feed additive augmenting, supporting the function of the nerve cells and nervous system and simultaneously minimizing, preventing the apoptosis of nerve cells and preventing the development of diseases of nervous system in adolescent, adult and fetuses in mammals, including people, such as Alzheimer, Parkinson, Huntington, Creutzweld-Jakob, BSE and other diseases and protecting the nervous system function against its degeneration due to apoptosis of nerve cells in Alzheimer, Parkinson, Huntington, Creutzweld-Jakob, BSE and other diseases and protecting the growth and stimulating the reproduction and preventing the apoptosis of nerve and other cells in vitro and in biotechnological processes with the use of somatic and bacterial cells . |