| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8f73183a541835b96a833faac40ea5c8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6d428ace14bae8ace34e2c2e441c6c9e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ab50d115f0e41c4fb3b016ad91d8bf3d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e85ec8f2eb480229c2d4a3da9e5d763d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f47d9a92c0cd9425db7ddf08e370f0d9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_93d5185cf124007d08a3587a8c5910f1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_114e4423ec77cbc8dab9d0a98909704e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_133245c7042332cf7ea2e6b2434f6a31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d21cdd6c9aa2a56078633fd99c1537ae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f0cbf06ce12d506f298287c139ab659d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-20134
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-20122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-517 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8258
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-205 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-145
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-82 |
| filingDate |
2005-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7f22bfb395fc3c07c8b0b5832c69072
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_854e944bdb4270d5ab8d3470210a7349
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9753cebf45f12974c82a2687ffe58978
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_447e3f36602a424a747da9977f0826f1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c8fb07a608915f666a3011748e8cf75
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad208d007f2035e1c03aa00de146e652
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ab8cd137ecd974e647f614315943088 |
| publicationDate |
2006-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2006016380-A3 |
| titleOfInvention |
A chimeric g protein based rabies vaccine |
| abstract |
A novel chimeric envelope coat protein of rabies virus was strategically designed to express a chimeric G protein at a high level in transgenic plants. A gene was theoretically designed and chemically synthesised to encode the chimeric G protein and expressed at high level in plant tissue. The gene was expressed in transgenic tobacco plants to examine its therapeutic efficacy against infection by rabies virus. The chimeric G protein was enriched in plant membranes. The BalbC mice were immunised with the plant leaf expressed G-protein. Commercially available killed rabies virus vaccine served as positive control. Plant derived chimeric G protein elicited higher immune response as compared to the commercial vaccine. The mice displayed protective immunity when they were challenged with live virus.Chimeric G protein expressed at high level in plant leaves was demonstrated to function as a commercially valuable subunit vaccine against rabies virus infection. It is very valuable for rabies management in human, pets and wild life. Further, edible part of such transgenic plants or the purified protein may also be useful as oral vaccine. |
| priorityDate |
2004-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |