http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006015796-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c6ac866067acd3f417b7cfc68b889ec6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_96c791045d8fea0357b2e7e3412cec0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_63b23bc4a0d611901b0e18e23e3c6d84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_adee240ecee232cf3f012d9149c69f2e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-538 |
| filingDate | 2005-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_759fa5285edac5391a8c887825e4e87b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_019f9f5dd4289166d3b937956a5cd3f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e64f46e9a6bd4af1dbe32d480b582b56 |
| publicationDate | 2006-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2006015796-A1 |
| titleOfInvention | Method for high-throughput screening of test molecules binding to target molecules |
| abstract | This invention relates to a method for identifying one or more molecules binding to a target molecule in a mixture of one or more test molecules, each test molecule having at least one known characteristic property, wherein the method comprises the following steps: (a) bringing said one or more test molecules into contact with said target molecule under conditions allowing formation of a complex comprising said target molecule and the molecule(s) binding to said target molecule; (b) separating said complex from the non-binding test molecule(s); (c) breaking said complex by changing the conditions; (d) separating the target molecule from the molecule(s) bound to the target molecule in step (a); and (e) detecting said molecule(s) bound to the target molecule in step (a) and separated therefrom in step (d) via its/their known property/ies, thereby identifying said molecule(s) binding to said target molecule, wherein separation in step (b) and/or step (d) is effected by size exclusion chromatography, whereby the matrix used for size exclusion chromatography is a copolymer of divinylbenzene and a hydrophilic monomer carrying a vinyl group such as N-vinylpirrolidone or a methacrylate, or a derivative of said copolymer. In a preferred embodiment, detection is effected by mass spectrometry. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10976310-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11071927-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017207460-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102346785-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190013999-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109219750-A |
| priorityDate | 2004-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 96.