abstract |
This invention relates to a process of stereoselectively synthesizing an alcohol of the following formula: (I) wherein Rl, R2, R3, R4, and R5 are defined in the specification. The process includes reacting (R) 4-formyl-2,2-dimethyldioxolane with α-bromoacetate in the presence of Zn and a Zn activating agent. |