abstract |
The invention provides, among other things, novel cell populations of CD133-cells. Some aspects of the invention provide endothelial generating cells (EGCs), such as, for example, CD34-CD133-CD73-CD14+CD11b+CXCR4+ cells, The invention further provides related compositions, kits and methods of isolating the novel EGC cell populations. Also provided by the invention are methods of inducing vascularization is subjects in need thereof, such as in subjects afflicted with ischemia or vascular occlusion, by administering to the subject the EGCs alone or in combination with other cell populations, polypeptides, compounds or other agents. |