| abstract |
The invention relates to a method of treating thrombus related diseases, such as variant angina, acute coronary syndromes, transient ischemic attack, brain stroke, peripheral arterial occlusive disease, and the like, comprising administering a histamine H1, receptor specific antagonist, and the use of histamine H1, receptor specific antagonists in such a treatment and in the manufacture of medicaments for treating thrombus related diseases. The invention is based on the fact that tissue factor initiating thrombus formation is induced by histamine. |